What is Profhilo®?
Hyaluronic Acid Skin Booster is an injectable skin remodelling treatment made with a stabilised hyaluronic acid formulation. Unlike traditional dermal fillers that add volume or structure, it works by hydrating the skin and support natural collagen and elastin production.
It is FDA-approved, CE-marked, and widely recognised bio-remodelling treatment for addressing concerns related to skin quality and visible signs of ageing.
In short, Profhilo is:
- NOT a filler
- Hyaluronic Acid (HA) injectable treatment
- “Bio-remodelling” effect to improve SKIN QUALITY
- 2 sessions
- Every 6-9 months
- Skin Booster
How Profhilo® Singapore Works?
Profhilo uses NAHYCO® Hybrid Technology, which combines two types of hyaluronic acid:
- Low molecular weight HA for hydration and skin suppleness.
- High molecular weight HA for longer-lasting structure and support.
When it is injected just below the skin’s surface, the HA booster spreads evenly across the treatment area, activating four key types of collagen and elastin.
Who Is The HA Skin Booster Suitable For?
It is for men and women experiencing:
- Early signs of skin ageing (fine lines, dullness, loss of elasticity)
- Dry, crepey skin texture
- Mild skin laxity in the face, neck, or hands
- Desire for natural-looking results without altering facial structure
It is commonly considered by adults aged 30–60 but can also be used preventively in younger patients to maintain skin quality.
Benefits of HA Skin Booster Treatment
- Intense Hydration – Support skin moisture levels.
- Support Elasticity – Stimulates natural collagen and elastin.
- Even Skin Tone & Texture – Address fine lines and uneven tone.
- Non-Volumising – No change to facial shape, just healthier skin.
HA Booster vs Dermal Fillers: What’s the Difference?
- Dermal Fillers: Add volume and contour to certain areas of the face (e.g. cheeks, lips, jawline).
- Profhilo: Does not change facial shape but instead improves overall skin quality through hydration and bio-remodelling.
Many patients choose the hyaluronic acid booster injections alongside fillers as part of a comprehensive plans related to skin quality and visible signs of ageing.
What to Expect During and After the HA booster Procedure
- During Treatment: Profhilo is injected at 5 precise points on each side of the face using a specialised technique called the BAP (Bio Aesthetic Points). The procedure takes around 10–15 minutes.
- After Treatment: Small bumps may appear at injection sites but they usually resolve within 24 hours as the product spreads naturally under the skin.
- Downtime varies between individuals. Many individuals are able to resume daily activities shortly after treatment.
How Many Sessions of Hyaluronic Acid Skin Boosters Are Needed?
- Initial Course: This comprises typically 2 sessions, spaced 4 weeks apart.
- Maintenance: Maintenance sessions are carried out every 6–12 months, depending on skin condition and ageing concerns.
Changes in skin appearance may develop gradually over several weeks.
Side Effects of the HA Booster and Its Downtime
It is administered following medical assessment by trained doctors. However, some temporary side effects may include:
- Mild redness or swelling at injection sites
- Small, visible bumps (resolve within 24–48 hours)
- Rare cases of bruising
No anaesthesia or downtime is required for hyaluronic acid booster injections.
Why Choose Aeon Medical for HA Booster Treatment?
At Aeon Medical, our treatments are doctor-led and tailored to your skin’s unique needs. We use CE-marked Profhilo products in accordance with medical practice guidelines.
With years of expertise in aesthetic medicine, we combine Profhilo with evidence-based protocols for natural-looking treatment outcomes.
Book a Consultation with Us For Hyaluronic Acid Booster Injections Ready to restore your skin’s natural glow?
Book a HA booster treatment consultation at Aeon Medical today and let our doctors design a treatment plan tailored to your needs.
Frequently Asked Questions (FAQs) About Profhilo® Treatment in Singapore
It is a stabilised hybrid complex formulated with a high concentration of 64mg/2ml, 100% pure Hyaluronic Acid, which is thermally cross-linked through the patented NAHYCO® Hybrid Technology.
The high and low molecular weight Hyaluronic Acid molecules bind themselves through a myriad of bonds, forming new stabilised hybrid cooperative complexes without the use of chemical BDDE cross-links which can cause other side effects. This new complex lasts in the skin for a longer period compared to non-cross-linked HA. It also does not impair the renewal of adipocytes (fats) stem cells in the skin.
Treatment leads to the remodelling of the Extra-Cellular Matrix (ECM) in terms of elasticity and support, which promotes and maintains the viability of fibroblasts (cells that produce HA and collagen), keratinocyctes (skin cells), and adipocytes (fat cells).
- Uses 100% pure hyaluronic acid
- Combination of 32mg of hyaluronic acid (high molecular weight) and 32mg of hyaluronic acid (low molecular weight)
- Stimulates elastin and collagen
- Addresses signs of skin ageing gradually, naturally
Some individuals may notice changes in skin hydration within several weeks. Furthermore, skin firmness and elasticity continue to improve over the following months.
- Fewer injection points (5 per cheek; 10 for neck)
- Bumps can subside within 24 hours
- High concentration HA (64mg/2ml)
- High and Low Molecular weight HA combination
- NO BDDE cross-links (uses patented thermal energy to link molecules)
- Stimulates elastin in the skin in addition to collagen for elasticity
- Stimulates Adipose-derived Stem Cells (ASC) which contribute to healing and maintaining skin structure and function
HA Boosters can be injected into the cheeks and neck areas. Our aesthetic doctor at Aeon Medical, Dr. Jeslin, will analyse and assess your skin condition and needs to determine the specific areas for treatment.
It is injected into or below the lower part of the deep skin layer (dermis) where pain can be more intense. A numbing cream will be applied prior to the treatment to reduce the pain, but mild-moderate pain can still be felt during the injection (depending on the individual variance of pain threshold). However, there are only 5 points of injection per cheek and 10 sites for the neck which is less than traditional skin booster treatments.
After cleansing by our trained therapist, numbing cream will be applied to the areas to be treated for about 30 minutes. After the numbing cream is removed, the procedure itself will take about 10-20 minutes depending on the number of areas to be treated. After the injection treatment, you will be brought back to your private room for a post-care treatment to enhance the recovery process. The total time needed may be 1 – 1.5 hours in the clinic.
You may have multiple swellings (“bumps”) and some redness on the injection sites for 1-2 days after the treatment. You are advised to stay indoors for 24-48 hours after the treatment to avoid external damage from the sun, pollutants, or cosmetics. The visible “bumps” will usually subside within 24 hours.
You should not apply make-up for 24-48 hours to avoid unnecessary clogging of the injection sites, which may lead to acne or infection. You should also avoid prolonged exposure to sunlight, and extreme temperatures, using saunas or Turkish baths, massages, and strenuous exercise for one week after the injection.
It is suitable for most skin types and tones, with a safety profile when administered by trained doctors. The HA Booster is US FDA approved and has the European CE mark approval.
It is a hyaluronic acid gel, but in a less viscous state to allow the product to spread and distribute in a wider area. Other types of hyaluronic acid gel fillers are thicker (more viscous) and are mainly used to replace volume in specific small areas.
HA injectable may be associated with certain reported side effects. While product characteristics such as viscosity or structure can differ among HA injectables, it is important to be aware of the potential adverse events reported for HA treatments and discuss them with a qualified healthcare professional.
Early side effects in the treated areas may include:
- Pain
- Tenderness
- Redness
- Swelling
- Bruising
- Itching
These side may subside within 2-3 days, but some symptoms like swelling or bruising can last up to 10-14 days or longer.
Late side effects of HA at the injection sites may appear weeks or even months after the procedure. They include:
- Discolouration of the skin
- Granulomas (accumulation of hardened tissue)
- Delayed allergic reactions
Rarer and more serious complications include:
Abscesses: Hard and swollen sores that may contain pus which requires surgical drainage and subsequent scarring
Blocking of blood vessels, which may be permanent, causing necrosis (damage/death of skin), blindness, or stroke
These complications are more relevant when injecting “thicker” HA fillers to localised areas in “bolus” for volume enhancement, especially around the nose and eye areas.
A safety assessment of PROFHILO® published on 22 June 2020 (Cassuto et al., Safety Assessment of High- and Low-Molecular Weight Hyalurons (Profhilo®) as Derived from Worldwide Postmarketing Data, BioMed Research International, Vol 2020, Article ID 8159047, 9 pages) showed 12 adverse events from over 40,000 patients (and almost 300,000 syringes sold) from February 2015 to February 2018. Early-onset reactions such as swelling, redness, and bruising along with late-onset reactions such as swelling and nodules were reported. “In no case was the product held liable for direct damage.” All 12 events were resolved without any complications.
Yes, it can be combined with other aesthetic treatments as it works well alongside Botox, dermal fillers, or laser treatments for a comprehensive anti-ageing approach.
On average, results may last 6–12 months after the treatment, depending on lifestyle, age, and skin condition.
Disclaimer
The information provided on this website is for educational purposes only and is, in no way, intended to be a substitute for professional medical advice, diagnosis, or treatment. We make no representation or warranty of any kind regarding the accuracy, availability, adequacy, or validity of the information or procedures outlined on the website. Always consult professional medical and aesthetic advice for your skincare and medical concerns.
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